BEX2 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction Overexpression of the gene may

Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation

The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide

The gene is part of a cluster of MMP genes which localize to chromosome 11q22

cytoskeletal reorganization

binds DNA as a dimer

BEX2 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction Overexpression of the gene mayThis gene belongs to the brain expressed X linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA binding complex that recognizes the E box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti proliferative effect