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VEGI Polyclonal Antibody, 20ul[BT-AP09510] Protein Expression Mutations in this gene have

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VEGI Polyclonal Antibody, 20ul[BT-AP09510] Protein Expression Mutations in this gene haveTumor necrosis factor ligand superfamily member 15 encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL 1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21 DR6. It can activate NF kappaB and MAP kinases, and acts as

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Description

Mutations in this gene have been linked with Li-Fraumeni syndrome

The E2F proteins contain several evolutionally conserved domains found in most members of the family

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

This channel consists of two subunits

Pro-apoptotic

VEGI Polyclonal Antibody, 20ul[BT-AP09510] Protein Expression Mutations in this gene haveTumor necrosis factor ligand superfamily member 15 encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL 1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21 DR6. It can activate NF kappaB and MAP kinases, and acts as

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