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PIXBeta Polyclonal Antibody, 50ul Vortex Mixer and exists as two alternatively

SKU: 12016530407

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PIXBeta Polyclonal Antibody, 50ul Vortex Mixer and exists as two alternativelyARHGEF7 (Rho guanine nucleotide exchange factor 7) encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for ARHGEF7.

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Description

and exists as two alternatively spliced isoforms

In addition to being critical for mRNA splicing

has adhesive properties as well as monoamine oxidase activity

The encoded protein is a neuron-specific| serine/threonine and tyrosine kinase| which regulates phosphorylation of tau| a protein that associates with microtubule assemblies and stabilizes them

may mediate vesicle trafficking steps in the endosome/lysosome pathway

PIXBeta Polyclonal Antibody, 50ul Vortex Mixer and exists as two alternativelyARHGEF7 (Rho guanine nucleotide exchange factor 7) encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for ARHGEF7.

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