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SLP-76 Polyclonal Antibody, 100ul[BT-AP08366] Cell Screening and Imaging This gene localizes within the

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SLP-76 Polyclonal Antibody, 100ul[BT-AP08366] Cell Screening and Imaging This gene localizes within theSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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Description

This gene localizes within the class III region of the MHC on the short arm of chromosome 6

The N-terminal segment of this domain has a consensus motif for proprotein convertase processing

The splicing factor 3a heterotrimer includes subunits 1

The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family

the encoded protein is acidic

SLP-76 Polyclonal Antibody, 100ul[BT-AP08366] Cell Screening and Imaging This gene localizes within theSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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