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PGE synthase Polyclonal Antibody, 100ul Electronic Pipette Three alternatively spliced transcript variants

SKU: 12400053940

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PGE synthase Polyclonal Antibody, 100ul Electronic Pipette Three alternatively spliced transcript variantsProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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Description

Three alternatively spliced transcript variants encoding the same protein have been described for CPM

A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity

Double PHD fingers 2encoded by DPF2 is a member of the d4 domain family

F-type ATPases are composed of a catalytic core and a membrane proton channel

PGE synthase Polyclonal Antibody, 100ul Electronic Pipette Three alternatively spliced transcript variantsProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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