CKR-5(Phospho Ser349) Polyclonal Antibody, 100ul Recombinant Protein Expression PPP4C-PPP4R2

PPP4C-PPP4R2

An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes ALS2CR11

and thus activating caspase-3 activation

The mRNA of this gene is subject to multiple RNA editing events

The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates

CKR-5(Phospho Ser349) Polyclonal Antibody, 100ul Recombinant Protein Expression PPP4C-PPP4R2This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include