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IGF2 Polyclonal Antibody, 50ul Plasma It participates in the formation

SKU: 12997732818

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IGF2 Polyclonal Antibody, 50ul Plasma It participates in the formationThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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Description

It participates in the formation of the Membrane Attack Complex (MAC)

Among its related pathways are Translation Insulin regulation of translation and Wnt signaling pathway (KEGG)

Proteolytic processing is required to generate a mature subunit

This gene is expressed mainly in testis with weak expression in the brain

It is also cleaved by caspase-3 in vitro

IGF2 Polyclonal Antibody, 50ul Plasma It participates in the formationThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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