CKR-5(Phospho Ser349) Polyclonal Antibody, 50ul Lysosome 7-transmembrane G-protein coupled receptor that

7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway

It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN

but this repression is then overcome by differentiation signals

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and also as a coactivator of NF-kappaB-mediated transcription

CKR-5(Phospho Ser349) Polyclonal Antibody, 50ul Lysosome 7-transmembrane G-protein coupled receptor thatThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include