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PIAS 3 Polyclonal Antibody, 20ul Peptide Library CEP57 (centrosomal protein 57) encodes

SKU: 16818078484

4.3
EUR97.20 EUR117.20

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PIAS 3 Polyclonal Antibody, 20ul Peptide Library CEP57 (centrosomal protein 57) encodesPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.

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Description

CEP57 (centrosomal protein 57) encodes a cytoplasmic protein called Translokin

Promotes integrin alpha-5/beta-1 and fibronectin (FN) matrix assembly in breast cancer cells

The protein (branched chain ketoacid dehydrogenase kinase) encoded by BCKDK is found in the mitochondrion

It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells

The promoter polymorphism of IL12B has been reported to be associated with the severity of atopic and non-atopic asthma in children

PIAS 3 Polyclonal Antibody, 20ul Peptide Library CEP57 (centrosomal protein 57) encodesPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.

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