RB6I2 Polyclonal Antibody, 100ul Insect Expression Studies of this gene's mouse

Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation

Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism

This gene belongs to the more telomeric copy of the duplicated region

Contains 2 Calx-beta domains

This member is a cytosolic protein

RB6I2 Polyclonal Antibody, 100ul Insect Expression Studies of this gene's mouseThe protein encoded by this gene is a member of a family of RIM binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10; 12)(q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.