Bmi-1 Rabbit Polyclonal Antibody(F270), 20ul Mechanical Pipette 7-transmembrane receptor (GPCR) superfamily

7-transmembrane receptor (GPCR) superfamily

Naturally-occurring readthrough transcripts occur from this gene into the downstream gene

Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified

A point mutation in the mouse ortholog

GRB2 and SOS1

Bmi-1 Rabbit Polyclonal Antibody(F270), 20ul Mechanical Pipette 7-transmembrane receptor (GPCR) superfamilyThis gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is