Parkin(Phospho Ser131) Polyclonal Antibody, 50ul ssDNA Synthesis Multiple cysteine residues are necessary

Multiple cysteine residues are necessary for proper targeting to the plasma membrane

which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds

and the relief of torsional stress that occurs during DNA transcription and replication

It also plays a role in nuclear pre-mRNA retention and transcriptional repression

Small GTP-binding proteins of the RAB family

Parkin(Phospho Ser131) Polyclonal Antibody, 50ul ssDNA Synthesis Multiple cysteine residues are necessaryThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants