PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing ACVR1C is a type I

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family

The RefSeq Project has decided to create four representative RefSeq records

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle

PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing ACVR1C is a type IThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.