Human Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Buffers & Solutions The protein encoded by this

The protein encoded by this gene mediates sodium and chloride transport and reabsorption

PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor

but another polymorphism has been associated with increased plasma cholesterol levels

2001 [PubMed 11242035])

Mutations in this gene result in primary ciliary dyskinesia-24

Human Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Buffers & Solutions The protein encoded by thisProteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N terminus growth factors, extracellular matrix proteases modulating their activity.