NEIL2 Polyclonal Antibody, 100ul Peptide Modification This enzyme is a multifunctional

This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution

Among its related pathways are Complement and coagulation cascades and Immune System

The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia

The mature peptide may be further cleaved into additional products (PMID: 20367554)

cell junction formation and regulation of overall water homeostasis

NEIL2 Polyclonal Antibody, 100ul Peptide Modification This enzyme is a multifunctionalNEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002