RNase Z2 Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene have

Mutations in this gene have been associated with limb-girdle muscular dystrophy

Several transcript variants encoding two different isoforms have been found for this gene

is the processing of class I MHC peptides

2008 [PubMed 18310074])

Maximum RCF 3

RNase Z2 Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene haveThe protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C terminal domain with tRNA processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST 1), and reduced expression can suppress transforming growth factor beta induced growth arrest. Mutations in ELAC2 result in an