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NR2E1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Both this protein and E2F4

SKU: 22159504751

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NR2E1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Both this protein and E2F4The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene.

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Description

Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107

May play an important role in the developing brain and neuronal differentiation

the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

DYRK1A is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene

NR2E1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Both this protein and E2F4The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene.

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