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Integrin Alpha2 Polyclonal Antibody, 100ul Sampling Tubes CBL is a proto-oncogene that

SKU: 25423519331

4.6
PLN123.75 PLN147.75

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Integrin Alpha2 Polyclonal Antibody, 100ul Sampling Tubes CBL is a proto-oncogene thatITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.

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Description

CBL is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase

Among its related pathways are Transport to the Golgi and subsequent modification and Chaperonin-mediated protein folding

allowing for room temperature storage and easy ambient shipping

Multiple transcript variants encoding different isoforms have been identified

subunit:Homodimer

Integrin Alpha2 Polyclonal Antibody, 100ul Sampling Tubes CBL is a proto-oncogene thatITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.

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