Phospho-ATF-2 (T73) Polyclonal Antibody, 100ul Human Genome Knockout Libraries The protein encoded by DOK2

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

Mutations in this gene result in type 2 oculocutaneous albinism

Overexpression induces apoptotic cell death

Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

Cathepsin Z has also been known as cathepsin X and cathepsin P

Phospho-ATF-2 (T73) Polyclonal Antibody, 100ul Human Genome Knockout Libraries The protein encoded by DOK2ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and