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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This protein has been found

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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This protein has been foundLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Description

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

Belongs to the vinculin/alpha-catenin family

A pseudogene of this gene has been defined on chromosome 5

It is highly conserved in vertebrates and most abundantly expressed in the brain

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This protein has been foundLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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