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HUWE1 Polyclonal Antibody, 50ul Sealing Film It also interacts with and

SKU: 26804358530

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HUWE1 Polyclonal Antibody, 50ul Sealing Film It also interacts with andThis gene encodes a protein containing a C terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2 related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with

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Description

It also interacts with and is phosphoryated by serine/threonine kinase 25

it binds tenaciously to poly(C)

Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas

plasmids often carry genes such as antibiotic resistance genes and fluorescent protein genes

Interacts also with SIAH1 which promotes targeting for degradation

HUWE1 Polyclonal Antibody, 50ul Sealing Film It also interacts with andThis gene encodes a protein containing a C terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2 related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with

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