AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis The encoded protein may function

The encoded protein may function as a transcription factor

This gene is the putative transforming gene of avian sarcoma virus 17

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The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation

This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00312] DNA Oligo Synthesis The encoded protein may functionAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with