Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries Mutations in this gene result

Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy

GFRA4 is a candidate gene for RET-associated diseases

Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten| 1997

Trisomy 13

Alternatively spliced transcript variants encoding different isoforms have been found for RAD9A

Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries Mutations in this gene resultThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.