AF-4 Polyclonal Antibody, 100ul Cellular Cultivation & Health Management High levels of expression of

High levels of expression of this gene enhance the growth of many tumors

XPO4 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments (Lipowsky et al

It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system

The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1

also known as Tarui disease

AF-4 Polyclonal Antibody, 100ul Cellular Cultivation & Health Management High levels of expression ofAFF1 encodes a member of the AF4 lymphoid nuclear protein related to AF4 Fragile X E mental retardation syndrome family of proteins, which have been implicated in childhood lymphoblastic leukemia, Fragile X E site mental retardation, and ataxia. It is the prevalent mixed lineage leukemia fusion gene associated with spontaneous acute lymphoblastic leukemia. Members of this family have three conserved domains: an N terminal homology domain, an AF4