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TM138 Rabbit Polyclonal Antibody, 20ul Modification Enzymes The product of this gene

SKU: 32727521476

4.2
PLN97.20 PLN128.20

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TM138 Rabbit Polyclonal Antibody, 20ul Modification Enzymes The product of this geneThis gene encodes a multi pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants.

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Description

The product of this gene belongs to the CRE (cAMP response element)-binding protein family

Its FA12-2P rotor and SA02P2 & SA05P2 adapters make it versatile for a variety of tubes and plates

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins

An important paralog of this gene is CABLES1

TM138 Rabbit Polyclonal Antibody, 20ul Modification Enzymes The product of this geneThis gene encodes a multi pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants.

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