G Alpha i-3 Polyclonal Antibody, 50ul Cell Function Analysis The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed by furin to generate the mature receptor

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The protein encoded by this gene interacts with SH3 domain-containing proteins| binds mitotic arrest deficient 2 beta protein| and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

SARNP (SAP domain containing ribonucleoprotein) encodes a protein that is upregulated in response to various cytokines

G Alpha i-3 Polyclonal Antibody, 50ul Cell Function Analysis The encoded preproprotein is proteolyticallyGuanine nucleotide binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. GNAI3 encodes an alpha subunit and belongs to the G alpha family. Mutation in this gene, resulting in a gly40 to arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein coupled endothelin receptor