p53(Phospho Ser6) Polyclonal Antibody, 20ul Apoptosis & Autophagy Naturally occurring read-through transcription occurs

Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1

When overexpressed in mammalian cells

The encoded protein contains an N-terminal actin-binding domain

The protein has 7 transmembrane regions and is located on the cell surface

which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin)

p53(Phospho Ser6) Polyclonal Antibody, 20ul Apoptosis & Autophagy Naturally occurring read-through transcription occursThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.