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Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development It is involved in the

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Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development It is involved in theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system

p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain

it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration

an important hormone and neurotransmitter

This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes

Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development It is involved in theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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