PTH/PTHrP-R Monoclonal Antibody, 100ul Peptide Modification The encoded protein is involved

The encoded protein is involved in the differentiation of several cell types including adipocytes

some protein-coding and some not protein-coding

Its expression is regulated by IL2 activation of the cells

can bypass the interleukin 6 receptor (IL6R) and directly activate this protein

Mutations in this gene cause Charcot-Marie-Tooth disease| type 2A1

PTH/PTHrP-R Monoclonal Antibody, 100ul Peptide Modification The encoded protein is involvedThe protein encoded by this gene is a member of the G protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC),