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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging Alternative splicing generates additional isoforms

SKU: 3478439338

4.2
PLN141.00 PLN162.00

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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging Alternative splicing generates additional isoformsTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Alternative splicing generates additional isoforms of each of the five growth hormones

CDCA7 (cell division cycle associated 7) was identified as a c-Myc responsive gene

This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily

with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs

and is considered to be an oncogene

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging Alternative splicing generates additional isoformsTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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