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IGF-IR Polyclonal Antibody, 20ul[BT-AP04397] Recombinant Protein Expression Two transcript variants encoding different

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IGF-IR Polyclonal Antibody, 20ul[BT-AP04397] Recombinant Protein Expression Two transcript variants encoding differentIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

Two transcript variants encoding different isoforms have been found for NOTCH2

Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions

cell adhesion is stronger on the PC membrane and its higher pore density enables easier exchange of transmembrane substances

With a surface area of 25 cm² and a capacity of 50 mL

this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted

IGF-IR Polyclonal Antibody, 20ul[BT-AP04397] Recombinant Protein Expression Two transcript variants encoding differentIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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