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WSB2 Rabbit Polyclonal Antibody, 50ul Stepper Mouse NLRP3 contains an N-terminal

SKU: 35585179109

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SEK185.00 SEK216.00

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WSB2 Rabbit Polyclonal Antibody, 50ul Stepper Mouse NLRP3 contains an N-terminalThis gene encodes a member of the WD protein subfamily. The encoded protein contains five WD repeats spanning most of the protein and an SOCS box in the C terminus. The SOCS box may act as a bridge between specific substrate binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene.

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Description

Mouse NLRP3 contains an N-terminal Pyrin domain (aa 1-91) followed by a Nacht region (aa 216-532)

Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia

Mutations in this gene are associated with snowflake vitreoretinal degeneration

such as B cell activation

Flap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis

WSB2 Rabbit Polyclonal Antibody, 50ul Stepper Mouse NLRP3 contains an N-terminalThis gene encodes a member of the WD protein subfamily. The encoded protein contains five WD repeats spanning most of the protein and an SOCS box in the C terminus. The SOCS box may act as a bridge between specific substrate binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene.

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