LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences LIN54 is a component of

LIN54 is a component of the LIN| or DREAM| complex| an essential regulator of cell cycle genes (Schmit et al

Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis

GO annotations related to this gene include poly(A) RNA binding and tRNA binding

but appear to have divergent biological functions

while transcript variants initiating downstream of the interspersed NNAT gene (GeneID: 4826) are expressed from the paternal allele

LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences LIN54 is a component ofSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been