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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments This gene encodes a mitochondrial

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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments This gene encodes a mitochondrialThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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Description

This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria

inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK)

CX3CR1 functions with CD4 as a co-receptor for the HIV-1 virus envelope protein

Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments This gene encodes a mitochondrialThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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