PS-1 Polyclonal Antibody, 50ul Aspirating Pipets an E2A protein

an E2A protein

EIF4E acts as a proto-oncogene

Unique dual-function design with a "scraper-type" structure at the other end to provide access to every hard-to-reach corner

This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development

The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins

PS-1 Polyclonal Antibody, 50ul Aspirating Pipets an E2A proteinAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.