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Cdc25A(Phospho Ser75) Polyclonal Antibody, 50ul[BT-AP07488] Immune Cell Analysis Activity of this protein is

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Cdc25A(Phospho Ser75) Polyclonal Antibody, 50ul[BT-AP07488] Immune Cell Analysis Activity of this protein isCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

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Description

Activity of this protein is important in promoting the survival of dopaminergic neurons

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

Interacts with HPS5 and NISCH

3 and an unprocessed pseudogene has been assigned to 16p12-p11

Like ubiquitin

Cdc25A(Phospho Ser75) Polyclonal Antibody, 50ul[BT-AP07488] Immune Cell Analysis Activity of this protein isCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

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