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K-cadherin Polyclonal Antibody, 20ul[BT-AP10599] Human Genome Knockout Libraries GO annotations related to this

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K-cadherin Polyclonal Antibody, 20ul[BT-AP10599] Human Genome Knockout Libraries GO annotations related to thisThis gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

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Description

GO annotations related to this gene include poly(A) RNA binding and methylated histone binding

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the Catalytic activity is acquired

HLA-DOB belongs to the HLA class II beta chain paralogues

it was noted that similar loci elsewhere in the genome are likely

the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing

K-cadherin Polyclonal Antibody, 20ul[BT-AP10599] Human Genome Knockout Libraries GO annotations related to thisThis gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

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