RGRF1 Polyclonal Antibody, 50ul Cell Culture Dishes Mutations in this gene lead

Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane

NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells

This protein binds to all three of the tumor suppressor proteins pRB

BAM32 interacts with Ptdlns and PLC g2 and

RGRF1 Polyclonal Antibody, 50ul Cell Culture Dishes Mutations in this gene leadThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta gamma subunit. Mouse studies