Bax Polyclonal Antibody, 100ul[BT-AP06693] Stepper Mutations in this gene have

Mutations in this gene have been associated with medulloblastomas| secretory breast carcinomas and other cancers

This gene is a member of the kelch-like family

Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord

the gene also contains sequence encoding calcium-binding motifs found in all cadherins

It plays a crucial role in activation and differentiation of the B-cell

Bax Polyclonal Antibody, 100ul[BT-AP06693] Stepper Mutations in this gene haveThe protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage dependent anion