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MITF Polyclonal Antibody, 50ul Glassware Sets subunit:Self-associates and interacts with EIF3

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MITF Polyclonal Antibody, 50ul Glassware Sets subunit:Self-associates and interacts with EIF3MITF encodes microphthalmia associated transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz

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Description

subunit:Self-associates and interacts with EIF3 p170 subunit

Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene

The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm

such as the placenta and testis

This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance

MITF Polyclonal Antibody, 50ul Glassware Sets subunit:Self-associates and interacts with EIF3MITF encodes microphthalmia associated transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz

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