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Smad2 Polyclonal Antibody, 100ul[BT-AP08384] Cell Separation and Collection PYCARD encodes an adaptor protein

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Smad2 Polyclonal Antibody, 100ul[BT-AP08384] Cell Separation and Collection PYCARD encodes an adaptor proteinMothers against decapentaplegic homolog 2 encoded by SMAD2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) beta, and thus regulates multiple cellular

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Description

PYCARD encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD)

Mutations in this gene have been associated with thrombophilia due to protein C deficiency

see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation

Multiple polyadenylation sites of this gene have been reported

CoV uses its spike protein to recognize ACE2 as its receptors and mediate membrane fusion and virus entry into host cells(PMID: 32221306)

Smad2 Polyclonal Antibody, 100ul[BT-AP08384] Cell Separation and Collection PYCARD encodes an adaptor proteinMothers against decapentaplegic homolog 2 encoded by SMAD2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) beta, and thus regulates multiple cellular

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