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MMP1 (Cleaved-Ile271) Rabbit Polyclonal Antibody, 20ul Nucleic Acid Isolation & Purification PTM:Phosphorylated (Possible)

SKU: 41773576185

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MMP1 (Cleaved-Ile271) Rabbit Polyclonal Antibody, 20ul Nucleic Acid Isolation & Purification PTM:Phosphorylated (Possible)Catalytic activity: Cleavage of the triple helix of collagen at about three quarters of the length of the molecule from the N terminus at 775 Gly Ile 776 in the alpha 1(I) chain. Cleaves synthetic substrates and alpha macroglobulins at bonds where P1' is a hydrophobic residue. cofactor: Binds 2 zinc ions per subunit. cofactor: Binds 4 calcium ions per subunit. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion

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Description

PTM:Phosphorylated (Possible)

subcellular location:Localized to plasma membrane coated pits

An important paralog of this gene is CSRNP2

Although TPSD1 (tryptase delta 1) may be an exception

and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex

MMP1 (Cleaved-Ile271) Rabbit Polyclonal Antibody, 20ul Nucleic Acid Isolation & Purification PTM:Phosphorylated (Possible)Catalytic activity: Cleavage of the triple helix of collagen at about three quarters of the length of the molecule from the N terminus at 775 Gly Ile 776 in the alpha 1(I) chain. Cleaves synthetic substrates and alpha macroglobulins at bonds where P1' is a hydrophobic residue. cofactor: Binds 2 zinc ions per subunit. cofactor: Binds 4 calcium ions per subunit. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion

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