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AQP2 Polyclonal Antibody, 100ul ssDNA Synthesis Alternate splicing resultsi n multiple

SKU: 45141083953

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AQP2 Polyclonal Antibody, 100ul ssDNA Synthesis Alternate splicing resultsi n multipleAquaporin 2 (AQP2) is a water transport protein that forms water channels in kidney tubules and plays a predominant role in controlling organism water homeostasis. Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus. This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due, in part, to either nonfunctional or mislocalized AQP2 protein.

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Description

Alternate splicing resultsi n multiple transcript variants

The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle

it is very low in resting cells

ARF4 is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D

The C-C motif chemokine receptor 7 encoded by CCR7 is a member of the G protein-coupled receptor family

AQP2 Polyclonal Antibody, 100ul ssDNA Synthesis Alternate splicing resultsi n multipleAquaporin 2 (AQP2) is a water transport protein that forms water channels in kidney tubules and plays a predominant role in controlling organism water homeostasis. Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus. This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due, in part, to either nonfunctional or mislocalized AQP2 protein.

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