RUBIC Rabbit Polyclonal Antibody, 100ul Cellular Cultivation & Health Management WTAP encodes a WT1-associating protein

WTAP encodes a WT1-associating protein

Mutations of this gene are associated with Seckel syndrome

antibody discovery

Gene Ontology (GO) annotations related to this gene include clathrin light chain binding

Expression of this gene is activated by the phosphatase and tensin homolog

RUBIC Rabbit Polyclonal Antibody, 100ul Cellular Cultivation & Health Management WTAP encodes a WT1-associating proteinThe protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains an N terminal RUN domain and a C terminal DUF4206 domain. The RUN domain is involved in Ras like GTPase signaling and the DUF4206 domain contains a diacylglycerol (DAG) binding like motif. Mutation in this gene results in deletion of the DAG binding like motif and causes a