CD57 Polyclonal Antibody, 50ul[BT-AP02069] Sample Library Tubes and susceptibility to osteoarthritis

and susceptibility to osteoarthritis

The encoded protein is known to play a role in cystic fibrosis and Huntington's disease

which plays a critical role in nonsense-mediated mRNA decay (NMD)

Alternate splicing results in multiple transcript variants

A ZFP91-related pseudogene has also been identified on chromosome 2

CD57 Polyclonal Antibody, 50ul[BT-AP02069] Sample Library Tubes and susceptibility to osteoarthritisCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis