PAK1/2(Phospho-Ser199/204) Rabbit Polyclonal Antibody, 50ul Deep Well Plates Additional post-translational modifications occur to

Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds

The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family

pathfinding

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

PAK1/2(Phospho-Ser199/204) Rabbit Polyclonal Antibody, 50ul Deep Well Plates Additional post-translational modifications occur toThis gene encodes a family member of serine threonine p21 activating kinases known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.