FAK(Phospho Tyr577) Polyclonal Antibody, 100ul Microbial Genome Editing Overexpression of this gene product

Overexpression of this gene product may be associated with neoplastic transformation for some tumors

|subcellular location:Translocated into the nucleus upon activation by IFN-alpha/beta

Mouse studies suggest that this receptor is important for peripheral pain responses

facilitating signal transduction

Unlike the classical PKC isoenzymes

FAK(Phospho Tyr577) Polyclonal Antibody, 100ul Microbial Genome Editing Overexpression of this gene productThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal