MLK3(Phospho Ser674) Polyclonal Antibody, 50ul Recombinant Protein Dual purpose block

Dual purpose block

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins

The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA

The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division

Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q

MLK3(Phospho Ser674) Polyclonal Antibody, 50ul Recombinant Protein Dual purpose blockThe protein encoded by this gene is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF kappaB mediated by Rho family