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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Like MYOM1

SKU: 48955833403

4.3
USD97.20 USD140.20

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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Like MYOM1BRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

Like MYOM1

Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein

CGGBP1 (CGG triplet repeat binding protein 1) influences expression of the FMR1 gene (MIM 309550)

and is thought to play a role in the early stage of recombinational repair of DNA

They physically associate with both proteasomes and ubiquitin ligases

Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Like MYOM1BRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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