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Ksr-1 Polyclonal Antibody, 100ul Immunology The encoded protein directly interacts

SKU: 49113687796

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Ksr-1 Polyclonal Antibody, 100ul Immunology The encoded protein directly interactsKSR1 (kinase supressor of Ras) was identified from a genetic screen in Drosophila and C. elegans as a component of the Ras signaling pathway. KSR1 has a putative carboxy terminal kinase domain that lacks a key Lys residue for phospho group transfer. Although reports indicate that ceramide and EGF activate KSR1, other evidence demonstrates that KSR1 regulates Raf in a kinase independent manner. It is now widely accepted that KSR1 functions as a

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Description

The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100

A loss of function mutation in GPT2 has been associated with developmental encephalopathy

Considered to play a role in gender determination

The product of OXSR1 (oxidative stress responsive 1) belongs to the Ser/Thr protein kinase family of proteins

This gene encodes a DNA topoisomerase

Ksr-1 Polyclonal Antibody, 100ul Immunology The encoded protein directly interactsKSR1 (kinase supressor of Ras) was identified from a genetic screen in Drosophila and C. elegans as a component of the Ras signaling pathway. KSR1 has a putative carboxy terminal kinase domain that lacks a key Lys residue for phospho group transfer. Although reports indicate that ceramide and EGF activate KSR1, other evidence demonstrates that KSR1 regulates Raf in a kinase independent manner. It is now widely accepted that KSR1 functions as a

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